Buffalo Bills 2021 Schedule

WeekDateOpponentTime
1Friday, August 13, 2021at Detroit7:00 PM
2Saturday, August 21, 2021at Chicago1:00 PM
3Saturday, August 28, 2021Green Bay1:00 PM
    
WeekDateOpponentTime
1Sunday, September 12, 2021Pittsburgh1:00 PM
2Sunday, September 19, 2021at Miami1:00 PM
3Sunday, September 26, 2021Washington1:00 PM
4Sunday, October 3, 2021Houston1:00 PM
5Sunday, October 10, 2021at Kansas City8:20 PM
6Monday, October 18, 2021at Tennessee8:15 PM
7BYEBYEBYE
8Sunday, October 31, 2021Miami1:00 PM
9Sunday, November 7, 2021at Jacksonville1:00 PM
10Sunday, November 14, 2021at N.Y. Jets1:00 PM
11Sunday, November 21, 2021Indianapolis1:00 PM
12Thursday, November 25, 2021at New Orleans8:20 PM
13Monday, December 6, 2021New England8:15 PM
14Sunday, December 12, 2021at Tampa Bay4:25 PM
15Sunday, December 19, 2021CarolinaTBA
16Sunday, December 26, 2021at New England1:00 PM
17Sunday, January 2, 2022Atlanta1:00 PM
18Sunday, January 9, 2022Jets1:00 PM